Specific Info on Drugs That Interfere With Plavix

Plavix Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Plavix is combined with any of the drugs listed above.
 
CYP 2C19 Inhibitors
Plavix is metabolized into its active form by certain liver enzymes known as CYP 2C19 enzymes. Certain other medications inhibit these enzymes, perhaps decreasing the effectiveness of Plavix. In general, it is usually best to avoid taking Plavix with such medications.
 
Fluvastatin
Taking Plavix and fluvastatin together can increase the amount of fluvastatin in your blood, resulting in possible side effects. Check with your healthcare provider before taking fluvastatin and Plavix together.
 
Medications That Increase the Risk of Bleeding
Taking Plavix with medications like anticoagulants (blood thinners), other antiplatelet drugs, or any other type of medication that can increase the risk of bleeding may increase your risk of dangerous internal bleeding. Plavix is intended to be used along with aspirin in certain situations. Check with your healthcare provider if you are unsure if you should be taking aspirin with Plavix.
  
Phenytoin
Taking Plavix and phenytoin together can increase the amount of phenytoin in your blood, resulting in possible side effects. Check with your healthcare provider before taking phenytoin and Plavix together.
 
Tamoxifen
Taking Plavix and tamoxifen together can increase the amount of tamoxifen in your blood, resulting in possible side effects. Check with your healthcare provider before taking tamoxifen and Plavix together.
 
Tolbutamide
Taking Plavix and tolbutamide together can increase the amount of tamoxifen in your blood, resulting in possible side effects. Check with your healthcare provider before combining these medications.
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Plavix Medication Information

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